Pediatría – Infecciones respiratorias

Efecto comparativo entre una formula herbal y transfer factor en niños con infecciones respiratorias

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Aug;29(8):742-5.

[Clinical observation
of effect of jiawei yupingfeng mixture for prevention and treatment of 100
children with repeated respiratory tract infection].

[Article
in Chinese]

Wang SJJiao CYSun XD.

Department of Chinese Medicine,
Dalian Children’s Hospital, Liaoning. wsj6136@163.com

Abstract

OBJECTIVE: To
investigate the effect of Jiawei Yupingfeng Mixture (YPF) on repeated
respiratory tract infection (RRTI) and its impacts on T-cell subsets,
immunoglobulin and erythrocyte immune.

METHODS: Two
hundred children with RRTI were assigned equally to two groups, the test group
treated with YPF and the control group treated by transfer factor. The clinical
efficacy, and the changes of T-cell subsets, immunoglobulin and erythrocyte
immune before and after treatment were observed in 31 patients randomly
selected from each group.

RESULTS: After
treatment, the frequency of attacking was reduced and the course of attacking
was shortened significantly in the test group as compared with before treatment
and also with the control group (P < 0.01); IgG and IgA levels were improved
in both groups, but the improvement was more significant in the test group
(P<0.01, P<0.05); T-cell subsets indices, including CD3(+), CD4(+),
CD8(+) and CD4(+)/CD8(+) ratio, all improved in the test group significantly (P
<0.01), while in the control group, significant improvement only showed in
rising of CD3(+) and CD4(+) (P <0.05, P <0.01), comparison between groups
showed significant difference in terms of CD3(+), CD4(+) and CD8(+); in the
control group, levels of C3b, RFER and RFIR were changed significantly
(P<0.05, P<0.01), but the improvement of ICR was insignificant, while in
the test group, the above indices were significant improved as compared with
after treatment of the control group (P <0.01).

CONCLUSION: YPF
plays a preventive and therapeatic role in children with RRTI by way of
regulating the cellular and humoral immune.

PMID:
19848211 [PubMed - in process]

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